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Publications
Dernière mise à jour :
4 juillet 2005
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2005
Ghisdal P., Vandenberg G., Hamaide M.C., Wibo M.,
Morel N.
The diacylglycerol lipase
inhibitor RHC-80267 potentiates the relaxation to acetylcholine in rat
mesenteric artery by anti-cholinesterase action
Eur. J. Pharmacol. (in press) [abstract]
Vermeiren C., Najimi N.,
Vanhoutte, N., Tilleux, S., de Hemptinne I., Maloteaux J.M., Hermans E.
(2005)
Acute upregulation of
glutamate uptake mediated by mGluR5 in reactive
astrocytes.
J. Neurochem. 94,
405-416
Najimi N., Maloteaux J.M., Hermans E.
(2005)
Pertussis toxin-sensitive
modulation of glutamate transport by endothelin-1 type A receptors in
glioma cells
Biochim. Biophys. Acta
Biomembranes 1668, 195-202 [abstract]
Vermeiren C., Najimi N.,
Maloteaux J.M., Hermans E. (2005)
Molecular and functional
characterisation of glutamate transporters in rat cortical astrocytes
exposed to a defined combination of growth factors during in vitro
differentiation.
Neurochem. Int. 46, 137-147
[abstract]
2004
Vanhoutte N., de Hemptinne I.,
Vermeiren C., Maloteaux J.M., Hermans E. (2004)
In vitro differentiated
neural stem cells express functional glial glutamate
transporters.
Neurosci. Lett. 370, 230-235 [abstract]
Govaerts S.J., Hermans E.,
Lambert D.M. (2004)
Comparison of Cannabinoid
Ligands’ Affinities and Efficacies Using the Guanosine 5’-O-(g-[35S]-thio)triphosphate
([35S]-GTPgS)
Binding
in Murine Tissues and in
Human Recombinant Cannabinoid Receptors.
Eur. J. Pharm. Sci. . 23, 233-243. [abstract]
Race V., Marie S., Kienlen-Campard P., Hermans E.,
Octave J.N., Van den Berghe G., Vincent M.F. (2004)
Adenylosuccinate lyase
deficiency: study of physiopathologic mechanism(s).
Nucleosides Nucleotides
Nucleic Acids. 23 1227-9. [abstract]
de Hemptinne I., Vermeiren
C., Maloteaux J.M., Hermans E. (2004)
Induction of glial glutamate
transporters in adult
mesenchymal stem cells.
J. Neurochem. 91, 155-166 [abstract]
Bardai SE, Lyoussi B, Wibo M, Morel N.
(2004)
Comparative study of the
antihypertensive activity of Marrubium vulgare and of the dihydropyridine
calcium antagonist amlodipine in spontaneously hypertensive
rat.
Clin Exp Hypertens.
26,465-74. [abstract]
Govaerts S.J., Muccioli
G.G., Hermans E., Lambert D.M. (2004)
Evidence for neutral
antagonism of imidazolinedione derivatives at CB1 cannabinoid receptors in
rat cerebellum.
Eur. J. Pharmacol. 495, 43-653 [abstract]
El-Hilaly J., Lyoussi B.,
Wibo M., Morel N. (2004)
Vasorelaxant effect of
the aqueous extract of Ajuga iva in rat aorta.
J. Ethnopharmacol. 93, 69-74 [abstract]
El Bardai S., Hamaide M.C., Lyoussi B.,
Quetin-Leclercq J., Morel N., Wibo M. (2004)
Marrubenol
interacts with the phenylalkylamine binding site of the L-type calcium
channel..
Eur. J. Pharmacol. 492, 269-272. [abstract]
Krenek P., Morel N.,
Kyselovic J., Wibo M. (2004)
Amlodipine at high dose
increases preproendothelin-1 expression in the ventricles and aorta of
normotensive rats.
J. Hypertens. 22, 827-35
[abstract]
Pitsi D., Octave J.N.
(2004)
Presenilin 1 stabilises the C-terminal fragment of the amyloid
precursor protein independently of
gamma-secretase activity.
J. Biol. Chem. 279,
25333-25338 [abstract]
Hermans
E.
Generation of Model Cell
Lines Expressing Recombinant G-Protein-Coupled
Receptors.
Receptor Signal
Transduction Protocols 259, 137-154 (Humana Press - ISBN 1-58829-329-7)
[abstract]
Peeters M., Romieu P.,
Maurice T., Su T.P., Maloteaux J.M., Hermans E. (2004)
Involvement of
the sigma1 receptor in the modulation of dopaminergic transmission by
amantadine.
Eur. J. Neurosci.
19, 2212-2220
[abstract]
Pierrot N., Ghisdal P.,
Caumont A.S., Octave J.N. (2004)
Intraneuronal amyloid-1-42 production
triggered by sustained increase of cytosolic calcium concentration induces
neuronal death.
J. Neurochem. 88,
1140-1150 [abstract]
2003
Leroy K., Boutajangout
A., Richardson J., Octave J.N., Lovestone S., Anderton B.H., Brion J.P.
(2003) Mutant presenilin 1 proteins induce cell death and reduce
tau-dependent processes outgrowth.
Neurosci
Lett. 353, 226-30
[abstract]
El-Bardai S.,
Wibo M., Hamaide M.C., Lyoussi B., Quetin-Leclercq J., Morel N.
(2003)
Characterisation of
marrubenol, a diterpene extracted from Marrubium vulgare, as an L-type
calcium channel blocker.
Br. J.
Pharmacol. 140, 1211-6 [abstract]
Wibo M.
(2003)
Brain nitric oxide synthase in hypertension.
J Hypertens. 21, 1623-4 [commentary – no abstract available]
Ghisdal P., Vandenberg
G., Morel N. (2003)
Rho-dependent kinase is involved in
agonist-activated calcium entry in rat arteries.
J. Physiol. 551, 855-867
[abstract]
Geurts M., Maloteaux
J.M., Hermans E. (2003)
Altered
expression of regulators of G-protein signaling (RGS) RNAs in the striatum
of rats undergoing dopamine depletion.
Biochem. Pharmacol. 66, 1163-1170 [abstract]
Skrzydelski D., Lhiaubet
A.M., Lebeau A., Forgez P., Yamada M., Hermans E., William Rostene W.,
Pelaprat D. (2003)
Differential involvement of intracellular domains
of the rat NST1 neurotensin receptor in coupling to G proteins.
Mol. Pharmacol. 64, 421-429 [abstract]
Hermans E.
(2003)
Biochemical and pharmacological control of the
multiplicity of coupling at G protein coupled receptors.
Pharmacol. Therap. 99, 25-44 [abstract]
Peeters M., Maloteaux
J.M., Hermans E. (2003)
Distinct effects of amantadine and memantine on
dopaminergic transmission in the rat striatum.
Neurosci. Lett. 343, 205-209 [abstract]
El Bardai S., Morel N.,
Wibo M., Fabre N., Llabres G., Lyoussi B., Quetin-Leclercq J.
(2003)
The vasorelaxant activity of marrubenol and
marrubiin from Marrubium vulgare.
Planta Med. 69, 75-7 [abstract]
2002
Geurts M., Hermans E.,
Maloteaux J.M. (2002)
Opposite modulation of regulators of G protein
signalling-2 RGS2 and RGS4 expression by dopamine receptors in the rat
striatum.
Neurosci Lett.
333, 146-50 [abstract]
Pitsi D., Kienlen-Campard
P., Octave J.N. (2002)
Failure
of the interaction between presenilin 1 and the substrate of
gamma-secretase to produce Abeta in insect cells.
J Neurochem. 83,
390-9 [abstract]
Kienlen-Campard, P., Miolet,
S., Tasiaux, B. and Octave, J-N. (2002)
Intracellular amyloïd-beta 1-42, but not
extracellular soluble amyloïd-beta peptides, induces neuronal
apoptosis.
J. Biol. Chem. 277,
15666-70 [abstract]
Page, G., Chalon, S., Emond,
P., Maloteaux, J-M. and Hermans, E. (2002)
Pharmacological characterisation of
(E)-N-(3-iodoprop-2-enyl)-2-carbomethoxy-3beta-(4’-methylphenyl)
nortropane (PE2I) binding to the rat neuronal dopamine transporter
expressed in COS cells.
Neurochem. Int. 40,
105-113 [abstract]
Peeters, M., Page, G.,
Maloteaux, J-M. and Hermans E. (2002)
Hypersensitivity of dopamine transmission in the
rat striatum after treatment with NMDA receptor antagonist
amantadine.
Brain Res. 949,
32-41[abstract]
Piech, A., Massart, P-E.,
Dessy, C., Feron, O., Havaux, X., Morel, N., Vanoverschelde, J-L.,
Donckier, J. and Balligand, J-L. (2002)
Decreased expression of myocardial eNOS and
caveolin in dogs with hypertrophic cardiomyopathy.
Am. J. Physiol.
Heart Circ. Physiol. 282,
H219-H231 [abstract]
Najimi, M., Gailly, P.,
Maloteaux, J-M. and Hermans, E. (2002)
Distinct regions of C-terminus of the high affinity
neurotensin receptor mediate the functional coupling with pertussis toxin
sensitive and insensitive G-proteins.
FEBS Lett. 512, 329-333 [abstract]
Najimi, M., Maloteaux,
J-M. and Hermans, E. (2002)
Cytoskeleton-related trafficking of the EAAC1
glutamate transporter after activation of the Gq/11-coupled neurotensin
receptor NTS1.
FEBS Lett. 523,
224-228 [abstract]
Kienlen-Campard, P. and
Octave, J-N. (2002)
Correlation between beta-amyloid peptide production
and human APP-induced neuronal death.
Peptides 23, 1199-204 [abstract]
Monge-Argiles, J.A.,
Maloteaux, J.M., Van den Bergh, P., Sindic, C. (2002)
Peripheral multineuritis pointing at systemic
sarcoidosis
Neurologia 17, 110-112
[abstract]
2001
El-Bardai, S., Lyoussi, B.,
Wibo, M. and Morel, N. (2001)
Pharmacological evidence of hypotensive activity of
Marrubium vulgare and Foeniculum vulgare in spontaneously hypertensive
rat.
Clin.Exp.Hypertens. 23,
329-343 [abstract]
Emilien, G., Misteli, C.,
Aveaux, D. and Maloteaux, J.M. (2001)
Life after
sequencing.
Trends Biotechnol. 19,
246 [abstract]
Festy, F., Lins, L.,
Peranzi, G., Octave, J.N., Brasseur, R. and Thomas, A. (2001)
Is aggregation of beta-amyloid peptides a
mis-functioning of a current interaction process?
Biochim. Biophys. Acta 1546, 356-364
[abstract]
Ghisdal, P. and Morel, N.
(2001)
Cellular target of voltage and calcium-dependent K+
channel blockers involved in EDHF-mediated responses in rat superior
mesenteric artery
Br. J.
Pharmacol. 134, 1021-1028 [abstract]
Grisshammer, R. and Hermans,
E. (2001)
Functional coupling with Galpha(q) and
Galpha(i1) protein subunits promotes high-affinity agonist binding to the
neurotensin receptor NTS-1 expressed in Escherichia coli.
FEBS Lett. 493, 101-105 [abstract]
Hermans, E. and Challiss
R.A.J.(2001)
Structural, signalling and regulatory
properties of the group I metabotropic glutamate receptors: prototypic
family C G protein-coupled receptors.
Biochem. J. 359, 465-484
[abstract]
Krenek, P., Salomone, S.,
Kyselovic, J., Wibo, M., Morel, N. and Godfraind, T. (2001)
Lacidipine prevents endothelial dysfunction in
salt-loaded stroke-prone hypertensive rats.
Hypertension 37, 1124-1128 [abstract]
Kyselovic, J., Krenek,
P., Wibo, M. and Godfraind, T. (2001)
Effects
of amlodipine and lacidipine on cardiac remodelling and renin production
in salt-loaded stroke-prone hypertensive rats.
Br. J. Pharmacol.134, 1516-1522 [abstract].
Maloteaux, J.M. (2001)
Pharmacologie de la nicotine.
Louvain Med. 120,
S76-S80
Najimi, M., Hermans, E.,
Rostène, W. and Forgez, P. (2001)
Transcriptional regulation of the tyrosine hydroxylase
gene by neurotensin in human neuroblastoma CHP 212 cells.
Metab. Brain Dis.16, 165-174 [abstract]
Page, G., Peeters, M.,
Najimi, M., Maloteaux, J.M. and Hermans, E. (2001)
Modulation
of the neuronal dopamine transporter activity by the metabotropic
glutamate receptor mGluR5 in rat striatal synaptosomes through
phosphorylation mediated processes.
J. Neurochem. 76, 1282-1290
[abstract]
Robinet, E.A, Geurts, M.,
Maloteaux, J.M. and Pauwels, P.J. (2001)
Chronic
treatment with certain antipsychotic drugs preserves upregulation of
regulator of G-protein signalling 2 RNA in rat striatum as opposed to
c-fos mRNA.
Neurosci. Lett.
307, 45-48 [abstract]
Brion, J.P., Anderton, B.H., Authelet, M.,
Dayanandan, R., Leroy, K., Lovestone, S., Octave, J.N., Pradier, L.,
Touchet, N., Tremp, G. (2001)
Neurofibrillary tangles and tau
phosphorylation.
Biochem Soc Symp.
67, 81-8 [abstract]
Emilien, G., Durlach, C., Aveaux, D., Maloteaux,
J.M. (2001)
Dopamine D-3
agonists
Exp. Opin. Ther.
Patents.11, 1713-1728
2000
Emilien, G., Beyreuther, K.,
Masters, C.L. and Maloteaux, J.M. (2000)
Prospects
for pharmacological intervention in Alzheimer disease.
Arch.Neurol. 57, 454-459 [abstract]
Emilien, G., Maloteaux,
J.M., Beyreuther, K. and Masters, C.L. (2000)
Alzheimer
disease: mouse models pave the way for therapeutic opportunities.
Arch. Neurol. 57, 176-181
[abstract]
Emilien, G., Maloteaux,
J.M., Penasse, C., Goodeve, A. and Casimir, C. (2000)
Haemophilias: advances towards genetic engineering
replacement therapy.
Clin. Lab.
Haematol. 22, 313-323 [abstract]
Emilien, G., Ponchon, M.,
Caldas, C., Isacson, O. and Maloteaux, J.-M. (2000)
Impact of
genomics on drug discovery and clinical medicine.
Q. J. Med. 93, 391-423 [abstract]
Emilien, G., van Meurs, W.
and Maloteaux, J.M. (2000)
The
dose-response relationship in phase I clinical trials and beyond: use,
meaning, and assessment.
Pharmacol.
Ther. 88, 33-58 [abstract]
Gailly, P., Najimi, M. and
Hermans, E. (2000)
Evidence
for the dual coupling of the rat neurotensin receptor with pertussis
toxin-sensitive and insensitive G-proteins.
FEBS Lett. 483, 109-113 [abstract]
Ghisdal, P., Gomez, J.P. and
Morel, N. (2000)
Action of a NO donor on the
excitation-contraction pathway activated by noradrenaline in rat superior
mesenteric artery.
J. Physiol.
522 183-196 [abstract]
Gomez, J.-P., Ghisdal, P.
and Morel, N. (2000)
Changes of
the potassium currents in rat aortic smooth muscle cells during postnatal
development.
Pflügers Arch.- Eur. J.
Physiol. 441, 388-397 [abstract]
Hermans, E., Saunders, R.,
Selkirk, J.V., Mistry, R., Nahorski, S.R. and Challiss, R.A.
(2000)
Complex involvement of pertussis toxin-sensitive G
proteins in the regulation of type 1alpha metabotropic glutamate receptor
signaling in baby hamster kidney cells.
Mol. Pharmacol. 58, 352-360 [abstract]
Kienlen-Campard, P.,
Tasiaux, B. and Octave, J.N. (2000)
The
processing and biological function of the human amyloid precursor protein
(APP): lessons from different cellular models.
Exp.Gerontol. 35, 843-850 [abstract]
Maloteaux, J.-M. (2000)
Les maladies dues aux prions.
Louvain Méd. 119,
142-148
Mbongolo Mbella, E.G.,
Bertrand, S., Huez, G. and Octave, J.N. (2000)
A GG
nucleotide sequence of the 3' untranslated region of amyloid precursor
protein mRNA plays a key role in the regulation of translation and the
binding of proteins.
Mol. Cell.
Biol. 20, 4572-4579 [abstract]
Noel, F., Geurts, M. and
Maloteaux, J.M. (2000)
Selective
destruction of nigrostriatal dopaminergic neurons does not alter
[3H]-ryanodine binding in rat striatum.
Braz. J. Med. Biol. Res. 33, 237-240
[abstract]
Octave, J.N., Essalmani, R.,
Tasiaux, B., Menager, J., Czech, C. and Mercken, L. (2000)
The role of presenilin-1 in the gamma-secretase
cleavage of the amyloid precursor protein of Alzheimer's disease.
J. Biol. Chem. 275, 1525-1528
[abstract]
Page, G., Peeters, M.,
Maloteaux, J.M. and Hermans, E. (2000)
Increased
dopamine uptake in striatal synaptosomes after treatment of rats with
amantadine.
Eur. J. Pharmacol.
403, 75-80 [abstract]
Toussaint, O., Baret, P.V., Brion, J.-P., Cras, P.,
Collette, F., De Deyn, P.P., Geenen, V., Kienlen-Campard, P., Labeur, C.,
Legros, J.J., Nève, J., Octave, J.-N., Piérard, G.E., Salmon, E., van den
Bosch de Aguilar, P., Van der linden, M., Leuven, F.V. and Vanfleteren, J.
(2000)
Experimental gerontology in
Belgium: from model organisms to age-related pathologies.
Exp. Gerontol.
35, 901-906 [abstract]
1999
Brion, J.P., Tremp, G. and
Octave, J.N. (1999)
Transgenic
expression of the shortest human tau affects its compartmentalization and
its phosphorylation as in the pretangle stage of Alzheimer's
disease.
Am. J. Pathol. 154, 255-270
[abstract]
Emilien, G., Maloteaux,
J.M., Geurts, M., Hoogenberg, K. and Cragg, S. (1999)
Dopamine receptors--physiological understanding to
therapeutic intervention potential.
Pharmacol. Ther. 84, 133-156 [abstract]
Emilien, G., Maloteaux, J.M.
and Ponchon, M. (1999)
Pharmacological management of diabetes: recent
progress and future perspective in daily drug treatment.
Pharmacol. Ther. 81, 37-51 [abstract]
Arribas S., Costa R.,
Salomone S., Morel N., Godfraind T., and Mac Grath J. (1999)
Functional reduction and associated cellular
rearrangement in SHRSP rat basilar arteries are affected by salt load and
calcium antagonist treatment.
J.
Cereb. Blood Flow Metab.19, 517-527[abstract]
Geurts, M., Hermans, E.,
Cumps, J. and Maloteaux, J.M. (1999)
Dopamine
receptor-modulated [35S]GTPgammaS binding in striatum of
6-hydroxydopamine-lesioned rats.
Brain Res. 841, 135-142 [abstract]
Geurts, M., Hermans, E. and
Maloteaux, J.M. (1999)
Enhanced
striatal dopamine D(2) receptor-induced [35S]GTPgammaS binding after
haloperidol treatment.
Eur. J.
Pharmacol. 382, 119-127 [abstract]
Geurts, M., Hermans, E. and
Maloteaux, J.M. (1999)
Assessment
of striatal D1 and D2 dopamine receptor-G protein coupling by
agonist-induced [35S]GTP gamma S binding.
Life Sci. 65, 1633-1645 [abstract]
Ghisdal, P., Godfraind, T.
and Morel, N. (1999)
Effect of
nitro-L-arginine on electrical and mechanical responses to acetylcholine
in the superior mesenteric artery from stroke-prone hypertensive
rat.
Br. J. Pharmacol. 128,
1513-1523 [abstract]
Kanyonyo, M., Govaerts, S.J., Hermans, E., Poupaert,
J.H. and Lambert, D.M. (1999)
3-Alkyl-(5,5'-diphenyl)imidazolidineiones as new
cannabinoid receptor ligands.
Bioorg.
Med. Chem. Lett. 9, 2233-2236 [abstract]
Lambert, D.M., DiPaolo, F.G., Sonveaux, P., Kanyonyo,
M., Govaerts, S.J., Hermans, E., Bueb, J., Delzenne, N.M. and Tschirhart,
E.J. (1999)
Analogues and homologues
of N-palmitoylethanolamide, a putative endogenous CB(2) cannabinoid, as
potential ligands for the cannabinoid receptors.
Biochim. Biophys.
Acta 1440, 266-274 [abstract]
Massart, P.E., Donckier, J.,
Kyselovic, J., Godfraind, T., Heyndrickx, G.R. and Wibo, M.
(1999)
Carvedilol and lacidipine prevent cardiac hypertrophy
and endothelin-1 gene overexpression after aortic banding.
Hypertension 34, 1197-1201
[abstract]
Mody, N., Hermans, E.,
Nahorski, S.R. and Challiss, R.A. (1999)
Inhibition
of N-linked glycosylation of the human type 1alpha metabotropic glutamate
receptor by tunicamycin: effects on cell-surface receptor expression and
function.
Neuropharmacology 38,
1485-1492 [abstract]
1998
Emilien, G. and Maloteaux,
J.M. (1998)
Current therapeutic uses and potential of
beta-adrenoceptor agonists and antagonists.
Eur. J. Clin. Pharmacol. 53, 389-404
[abstract]
Emilien, G. and Maloteaux,
J.M. (1998)
Pharmacological management of epilepsy.
Mechanism of action, pharmacokinetic drug interactions, and new drug
discovery possibilities. Int. J.
Clin. Pharmacol. Ther. 36, 181-194
[abstract]
Hermans, E. and Maloteaux,
J.M. (1998)
Mechanisms of regulation of neurotensin
receptors.
Pharmacol. Ther. 79,
89-104 [abstract]
Kyselovic, J., Morel, N.,
Wibo, M. and Godfraind, T. (1998)
Prevention
of salt-dependent cardiac remodeling and enhanced gene expression in
stroke-prone hypertensive rats by the long-acting calcium channel blocker
lacidipine.
J. Hypertens. 16,
1515-1522 [abstract]
Macq, A.F., Czech, C.,
Essalmani, R., Brion, J.P., Maron, A., Mercken, L., Pradier, L. and
Octave, J.N. (1998)
The long
term adenoviral expression of the human amyloid precursor protein shows
different secretase activities in rat cortical neurons and
astrocytes.
J. Biol. Chem. 273,
28931-28936 [abstract]
Morel, N., Buryi, V., Feron,
O., Gomez, J.P., Christen, M.O. and Godfraind, T. (1998)
The action of calcium channel blockers on recombinant
L-type calcium channel alpha1-subunits.
Br. J. Pharmacol. 125, 1005-1012
[abstract]
Najimi, M., Souaze, F.,
Mendez, M., Hermans, E., Berbar, T., Rostene, W. and Forgez, P.
(1998)
Activation of receptor gene transcription is required
to maintain cell sensitization after agonist exposure. Study on
neurotensin receptor.
J. Biol. Chem.
273, 21634-21641 [abstract]
Salomone, S., Morel, N. and
Godfraind, T. (1998)
A
therapeutic dosage of amlodipine prevents vascular hyporeactivity induced
in rats by lipopolysaccharide.
Naunyn Schmiedeberg's Arch.
Pharmacol. 357, 252-259
[abstract]
Wibo, M., Feron, O., Zheng,
L., Maleki, M., Kolar, F. and Godfraind, T. (1998)
Thyroid
status and postnatal changes in subsarcolemmal distribution and isoform
expression of rat cardiac dihydropyridine receptors. Cardiovasc. Res. 37,
151-159 [abstract]
1997
Czech, C., Delaere, P.,
Macq, A.F., Reibaud, M., Dreisler, S., Touchet, N., Schombert, B.,
Mazadier, M., Mercken, L., Theisen, M., Pradier, L., Octave, J.N.,
Beyreuther, K. and Tremp, G. (1997)
Proteolytical processing of mutated human amyloid
precursor protein in transgenic mice.
Brain Res. Mol. Brain Res. 47, 108-116 [abstract]
Godfraind, T., Salomone, S., Morel, N. and Ghisdal, P.
(1997)
Etude préclinique de l'action
d'un anticalcique lors d'un regime riche en sel. [Preclinical study of the
action of a calcium channel blocker during salt load].
Bull. Acad. Natl. Med. 181, 289-298
[abstract]
Hermans, E., Geurts, M. and
Maloteaux, J.M. (1997)
Agonist
and antagonist modulation of [35S]-GTP gamma S binding in transfected CHO
cells expressing the neurotensin receptor.
Br. J. Pharmacol. 121, 1817-1823
[abstract]
Hermans, E., Vanisberg,
M.A., Geurts, M. and Maloteaux, J.M. (1997)
Down-regulation of neurotensin receptors after
ligand-induced internalization in rat primary cultured neurons.
Neurochem. Int. 31, 291-299
[abstract]
Jeanjean, A.P., Laterre,
E.C. and Maloteaux, J.M. (1997)
Neuroleptic binding to sigma receptors: possible
involvement in neuroleptic-induced acute dystonia.
Biol. Psychiatry 41, 1010-1019 [abstract]
Knoops, B. and Octave, J.N.
(1997)
Alpha 1-tubulin mRNA level is increased during neurite
outgrowth of NG 108-15 cells but not during neurite outgrowth inhibition
by CNS myelin.
Neuroreport 8, 795-798
[abstract]
Luabeya, M.K., Vanisberg,
M.A., Jeanjean, A.P., Baudhuin, P., Laduron, P.M. and Maloteaux, J.M.
(1997)
Fractionation of human brain by differential and
isopycnic equilibration techniques.
Brain Res. Brain Res. Protoc.1, 83-90
[abstract]
Maron, A., Havaux, N.,
Le-Roux, A., Knoops, B., Perricaudet, M. and Octave, J.N.
(1997)
Differential toxicity of ganciclovir for rat neurons
and astrocytes in primary culture following adenovirus-mediated transfer
of the HSVtk gene.
Gene Ther. 4,
25-31 [abstract]
Mottet, I., Demeure, R.,
Rataud, J., Lucas, M., Wahl, F., Warscotte, V., Thiran, J.P., Goudemant,
J.F., Maldague, B., Maloteaux, J.M. and Stutzmann, J.M. (1997)
Effects of riluzole on the evolution of focal cerebral
ischemia: a magnetic resonance imaging study.
MAGMA. 5, 185-191 [abstract]
Salomone, S., Morel, N. and
Godfraind, T. (1997)
Role of
nitric oxide in the contractile response to 5-hydroxytryptamine of the
basilar artery from Wistar Kyoto and stroke-prone rats.
Br. J. Pharmacol. 121, 1051-1058
[abstract]
1996
Emilien, G. and Maloteaux,
J.M. (1996)
Lithium neurotoxicity at low therapeutic
doses Hypotheses for causes and mechanism of action following a
retrospective analysis of published case reports.
Acta Neurol. Belg. 96, 281-293 [abstract]
Emilien, G., Maloteaux,
J.M., Seghers, A. and Charles, G. (1996)
Lithium
compared to valproic acid and carbamazepine in the treatment of mania: a
statistical meta-analysis.
Eur. Neuropsychopharmacol. 6, 245-252 [abstract]
Essalmani, R., Macq, A.F.,
Mercken, L. and Octave, J.N. (1996)
Missense
mutations associated with familial Alzheimer's disease in Sweden lead to
the production of the amyloid peptide without internalization of its
precursor.
Biochem.Biophys.Res.Commun. 218, 89-96 [abstract]
Essalmani, R., Guillaume,
J.M., Mercken, L. and Octave, J.N. (1996)
Baculovirus-infected cells do not produce the amyloid
peptide of Alzheimer's disease from its precursor.
FEBS Lett. 389, 157-161 [abstract]
Gailly, P., Hermans, E. and
Gillis, J.M. (1996)
Role of
[Ca2+]i in "Ca2+ stores depletion-Ca2+ entry coupling' in fibroblasts
expressing the rat neurotensin receptor.
J. Physiol. 491, 635-46 [abstract]
Hermans, E., Octave, J.N.
and Maloteaux, J.M. (1996)
Interaction of the COOH-terminal domain of the
neurotensin receptor with a G protein does not control the phospholipase C
activation but is involved in the agonist-induced internalization.
Mol.Pharmacol. 49, 365-372 [abstract]
Hermans, E. and Maloteaux,
J.M. (1996)
Desensitization of neurotensin-induced
phosphoinositide hydrolysis in transfected CHO cells.
Biochem. Pharmacol. 51, 1749-1752 [abstract]
Maron, A., Gustin, T.,
Le-Roux, A., Mottet, I., Dedieu, J.F., Brion, J.P., Demeure, R.,
Perricaudet, M. and Octave, J.N. (1996)
Gene
therapy of rat C6 glioma using adenovirus-mediated transfer of the herpes
simplex virus thymidine kinase gene: long-term follow-up by magnetic
resonance imaging.
Gene Ther. 3,
315-322 [abstract]
Philippe, B., Brion, J.P.,
Coppens, E. and Octave, J.N. (1996)
Generation
of a monoclonal antibody to the carboxy-terminal domain of tau by
immunization with the amino-terminal domain of the amyloid precursor
protein.
J. Neurosci. Res. 46,
709-719 [abstract]
Salomone, S., Dessy, C.,
Morel, N. and Godfraind, T. (1996)
Inhibition
by bosentan, an endothelin antagonist, of the hypersensitivity to Ca2+
channel activator evoked by salt-loading in basilar artery of stroke-prone
spontaneously hypertensive rats.
Life
Sci. 59, L247-L253 [abstract]
Salomone, S., Silva, C.L.,
Morel, N. and Godfraind, T. (1996)
Facilitation of the vasorelaxant action of calcium
antagonists by basal nitric oxide in depolarized artery.
Naunyn
Schmiedeberg's Arch. Pharmacol. 354, 505-512
[abstract]
Zheng, L., Wibo, M., Kolar,
F. and Godfraind, T. (1996)
Calcium
channels and cation transport ATPases in cardiac hypertrophy induced by
aortic constriction in newborn rats.
Mol. Cell. Biochem. 163-16423-9, 16423-16429
[abstract]
1995
Buryi, V., Morel, N.,
Salomone, S., Kerger, S. and Godfraind, T. (1995)
Evidence
for a direct interaction of thapsigargin with voltage-dependent Ca2+
channel.
Naunyn Schmiedeberg's Arch.
Pharmacol. 351, 40-45
[abstract]
Emilien, G., Maloteaux,
J.M., Seghers, A. and Charles, G. (1995)
Lithium
therapy in the treatment of manic-depressive illness. Present status and
future perspectives. A critical review.
Arch. Int. Pharmacodyn. Ther. 330, 251-278
[abstract]
Hermans, E., Gailly, P.,
Gillis, J.M., Octave, J.N. and Maloteaux, J.M. (1995)
Lack of rapid desensitization of Ca2+ responses in
transfected CHO cells expressing the rat neurotensin receptor despite
agonist-induced internalization.
J. Neurochem. 64, 2518-2525
[abstract]
Holemans, S., Feron, O.,
Octave, J.N. and Maloteaux, J.M. (1995)
Interaction of fluorescein derivatives with
glibenclamide binding sites in rat brain.
Neurosci.Lett. 183, 183-186 [abstract]
Jeanjean, A.P., Moussaoui,
S.M., Maloteaux, J.M. and Laduron, P.M. (1995)
Interleukin-1 beta induces long-term increase of
axonally transported opiate receptors and substance P.
Neuroscience 68, 151-157 [abstract]
Maloteaux, J.M., Luabeya,
M.K., Vanisberg, M.A., Jeanjean, A.P., Baudhuin, P., Scherman, D. and
Laduron, P.M. (1995)
Subcellular distribution of receptor sites in human
brain: differentiation between heavy and light structures of high and low
density.
Brain Res. 687,
155-166 [abstract]
Maron, A., Gustin, T.,
Mottet, I., Demeure, R. and Octave, J.N. (1995)
Ganciclovir mediated regression of rat brain tumors
expressing the herpes simplex virus thymidine kinase imaged by magnetic
resonance. J. Neurooncol. 24,
259-265 [abstract]
Octave, J.N.
(1995)
The amyloid peptide and its precursor in Alzheimer's
disease.
Rev. Neurosci. 6,
287-316 [abstract]
Octave, J.N.
(1995)
The amyloid peptide precursor in Alzheimer's
disease.
Acta Neurol. Belg. 95,
197-209 [abstract]
Salomone, S., Morel, N. and
Godfraind, T. (1995)
Effects of
8-bromo cyclic GMP and verapamil on depolarization-evoked Ca2+ signal and
contraction in rat aorta.
Br.
J. Pharmacol. 114, 1731-1737 [abstract]
Sam, E., Jeanjean, A.P.,
Maloteaux, J.M. and Verbeke, N. (1995)
Apomorphine pharmacokinetics in parkinsonism after
intranasal and subcutaneous application.
Eur. J. Drug Metab.
Pharmacokinet. 20, 27-33 [abstract]
Wibo, M., Kolar, F., Zheng,
L. and Godfraind, T. (1995)
Influence
of thyroid status on postnatal maturation of calcium channels,
beta-adrenoceptors and cation transport ATPases in rat ventricular
tissue.[abstract]
J. Mol. Cell.
Cardiol. 27, 1731-1743 [abstract]
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